Making pre-eclampsia

safer together

We believe in safety and dignity in pregnancy. We want to empower through clarity and information when complications arise.

About PIERSai™

Our goal is a world where clinicians, patients and their families work together in partnership to make informed decisions about each individual’s care.

That’s why we build tools that transform complex medical data into easy-to-understand, actionable insights. By making the risk in a frightening diagnosis clear and visual, we enable clear communication in healthcare and safety in supported decision making.

Our clinical decision support tool predicts adverse maternal outcomes in pre-eclampsia, grouping risks in a way that’s easy to interpret and use in patient conversations.

Our Technology

PIERSai™ builds on decades of research and global collaboration to provide risk assessment that is both evidence-based and adaptable to context.

By integrating data from a wide range of settings and updating predictions over time, it supports decision-making throughout a woman’s care, rather than at a single point in time. The aim remains to provide clearer, more reliable information in situations where decisions are complex, time-sensitive, and consequential for both mother and baby.

The Problem

Pregnancy hypertension complicates up to 13% of pregnancies (≈5 million pregnancies annually globally), and is associated
with ≈46,000 maternal and ≈500,000 perinatal deaths annually.

Across the globe, Black, immigrant, and deprived women are most likely to develop pre-eclampsia; such deprived/minoritised women are more likely to face life-threatening and life-ending complications. Pregnant women whose pregnancies are complicated by pregnancy hypertension and their maternity care providers make joint decisions regarding:

• Place of care • Co-interventions • Timing of birth.

Currently, such decisions are generally based on clinical gestalt.

Value Proposition

For Users

  • Standardised, dynamic, and evidence-based risk assessment across clinicians and sites

  • Reduced variation in care and improved auditability

  • Reduced cognitive load and ambiguity

  • Guidance in data-limited situations

  • Improved documentation and defensibility

  • Fewer adverse maternal outcomes (earlier intervention)

  • Alignment with national safety priorities

  • Geographically-naïve

  • Cost-effective

For Patients

  • Clear, visual understanding of risk

  • Contextualised comparisons with similar pregnancies

  • Improved communication and shared decision-making

  • Increased confidence

Our team

Prof Peter von Dadelszen

Prof Paul Murray

Dr Tunde Csoban

Claire Singleton

Prof Laura Magee

Prof Kim Kavanagh

Work with us

If you have any questions or would be interested in trialling the PIERSai™ dashboard in your practice, get in touch using the contact form below.

We are also open to academic collaborations and implementation
trials, do not hesitate to contact us if you think PIERSai™ could be useful
for your research!